GEO DataSets

(Submitter supplied) To compare different differential expression profile between malathion resistant and susceptible Cx. quinquefasciatus in Harris County and to identify candidate genes involved in matabolic detoxification of malathion

Organism:

Culex quinquefasciatus

Type:

Expression profiling by high throughput sequencing

Platform:

GPL32372

20 Samples

Download data: TXT

(Submitter supplied) We investigated genome folding across the eukaryotic tree of life. We find four general manifestations of genome organization at chromosome-scale that each emerge and disappear repeatedly over the course of evolution. The submission represents chromosome-length Hi-C contact maps, architecture type and homolog separation analyses for 26 species across the tree of life, representing all subphyla of chordates, all 7 extant vertebrate classes, and 7 out of 9 major animal phyla, as well as plants and fungi.

Organism:

Strongylocentrotus purpuratus; Ciona intestinalis; Pleurobrachia bachei; Acropora millepora; Python bivittatus; Saccharomyces cerevisiae; Drosophila melanogaster; Gallus gallus; Hypsibius dujardini; Lethenteron camtschaticum; Arachis hypogaea; Agaricus bisporus; Branchiostoma lanceolatum; Xenopus laevis; Notamacropus eugenii; Pygocentrus nattereri; Cristatella mucedo; Clonorchis sinensis; Chiloscyllium punctatum; Triticum aestivum; Caenorhabditis elegans; Aplysia californica; Aedes aegypti; Culex quinquefasciatus; Homo sapiens; Muntiacus reevesi; Muntiacus muntjak

Type:

Other

30 related Platforms

32 Samples

Download data: BEDPE, FASTA, HIC, VCF, WIG

(Submitter supplied) The human transcription factor (TF) CGGBP1 (“CGG Binding Protein”) is conserved only in amniotes, and is believed to derive from the zf-BED and Hermes transposase DNA-binding domains (DBDs) of a hAT DNA transposon. Here, we examine the DNA binding preferences of a wide variety of metazoan CGGBP1-like TFs with this bipartite domain using PBM experiments. The derived motifs are available at ...

Organism:

Aedes aegypti; Culex quinquefasciatus; Latimeria chalumnae; Cyprinus carpio; synthetic construct; Hucho hucho; Amphiprion ocellaris; Labeo rohita; Mola mola; Sphaeramia orbicularis; Anabarilius grahami; Petromyzon marinus; Acipenser ruthenus; Gallus gallus; Erpetoichthys calabaricus; Rhizophagus irregularis; Paramormyrops kingsleyae; Locusta migratoria; Crocodylus porosus; Homo sapiens; Rhodnius prolixus; Rhipicephalus appendiculatus; Kryptolebias marmoratus; Nematostella vectensis; Acanthochromis polyacanthus; Hippocampus comes; Hofstenia miamia; Acyrthosiphon pisum; Salmo salar; Fundulus heteroclitus; Sparus aurata; Chrysemys picta; Austrofundulus limnaeus; Anabas testudineus; Amphiprion percula; Salarias fasciatus

Type:

Other

Platform:

GPL11260

258 Samples

Download data: TXT

(Submitter supplied) Determination of miRNA profiles in most prominent mosquitoes will determine the potential targets for mosquito control Some of the most medically important viruses, such as dengue virus, West Nile virus, Zika virus, and yellow fever virus, are transmitted by mosquitoes. These aptly named arboviruses impose a tremendous cost to the health of populations around the world. As a result, much effort has gone into the study of the impact of these viruses in human infections. more...

Organism:

synthetic construct; Aedes aegypti; Culex quinquefasciatus

Type:

Non-coding RNA profiling by array

Platform:

GPL21572

2 Samples

Download data: CEL

(Submitter supplied) We present an integrated resource of profiling and analysis of small RNAs from mosquiot cells and tissues from 4 main species to determine how the viruses and transposons compare in the production of small regulatory RNAs.

Organism:

Aedes albopictus; Aedes aegypti; Anopheles gambiae; Culex quinquefasciatus

Type:

Non-coding RNA profiling by high throughput sequencing

4 related Platforms

54 Samples

Download data: TXT

(Submitter supplied) Anopheles gambiae mosquitoes transmit the human malaria parasite Plasmodium falciparum, which causes the majority of fatal malaria cases worldwide. The hematophagous life style defines the mosquito reproductive biology and is exploited by P. falciparum for its own sexual reproduction and transmission. The two main phases of the mosquito reproductive cycle, pre-vitellogenic (PV) and post-blood meal (PBM) shape its capacity to transmit malaria. more...

Organism:

Tribolium castaneum; Aedes aegypti; Anopheles gambiae; Culex quinquefasciatus; Apis mellifera; Bombyx mori; Drosophila melanogaster

Type:

Non-coding RNA profiling by array

Platform:

GPL23950

40 Samples

Download data: TXT

(Submitter supplied) The Zika outbreak, spread by the Aedes aegypti mosquito, highlights the need to create high-quality assemblies of large genomes in a rapid and cost-effective fashion. Here, we combine Hi-C data with existing draft assemblies to generate chromosome-length scaffolds. We validate this method by assembling a human genome, de novo, from short reads alone (67X coverage, Sample GSM1551550). We then combine our method with draft sequences to create genome assemblies of the mosquito disease vectors Aedes aegypti and Culex quinquefasciatus, each consisting of three scaffolds corresponding to the three chromosomes in each species. more...

Organism:

Aedes aegypti; Culex quinquefasciatus; Homo sapiens

Type:

Other; Third-party reanalysis

Platforms:

GPL22030 GPL22042

3 Samples

Download data: FASTA, TXT

(Submitter supplied) Lysinibacillus sphaericus produces the mosquito larvicidal binary toxin consisting of BinA and BinB, which are both required for toxicity against Culex and Anopheles larvae. The molecular mechanisms behind Bin toxin-induced damage remain unexplored. We used whole-genome microarray-based transcriptome analysis to better understand how Culex larvae respond to Bin toxin treatment at the molecular level. more...

Organism:

Culex quinquefasciatus

Type:

Expression profiling by array

Platform:

GPL10712

12 Samples

Download data: TXT

(Submitter supplied) DNA methylation is an important chromatin modification that is necessary for the structural integrity and proper regulation of the genome for many species. Despite its conservation across the tree of life, little is known about its contribution to complex traits. Reports that differences in DNA methylation between castes in closely related Hymenopteran insects (ants, bees and wasps) contributes to social behaviors has generated hypotheses on the role of DNA methylation in governing social behavior. more...

Organism:

Blattella germanica; Periplaneta americana; Helicoverpa zea; Aedes albopictus; Aedes atropalpus; Rhyparobia maderae; Cryptocercus garciai; Aphis craccivora; Aedes aegypti; Anopheles gambiae; Culex quinquefasciatus; Reticulitermes virginicus; Pemphigus obesinymphae; Blaptica dubia; Pemphigus populitransversus; Microplitis mediator; Chrysodeixis includens; Acyrthosiphon pisum; Anastrepha suspensa; Aphidius ervi; Toxorhynchites amboinensis; Pemphigus populicaulis; Pyractomena borealis; Heliothis virescens; Copidosoma floridanum; Eublaberus posticus; Reticulitermes flavipes; Microplitis demolitor; Polistes carolina; Blattella asahinai

Type:

Methylation profiling by high throughput sequencing

30 related Platforms

69 Samples

Download data: TXT

(Submitter supplied) The Southern house mosquito, Culex quinquefasciatus, is a vector of the causative agents of many diseases including West Nile Fever, St. Louis Encephalitis, and lymphatic filariasis. In order to manage the spread of these diseases, vector control efforts rely heavily on insecticides, including pyrethroids, namely permethrin. In our study we investigated the changes in the gene expression profiles of a highly-permethrin resistant strain of Cx. more...

Organism:

Culex quinquefasciatus

Type:

Expression profiling by high throughput sequencing

Platform:

GPL14891

4 Samples

Download data: TXT

(Submitter supplied) The Southern house mosquito, Culex quinquefasciatus, is an anautogenous mosquito species that requires a blood meal in order to provision the eggs. Following the eclosion of the adults from the pupal stage, adult female mosquitoes require a period of time for mating and development before they are competent to take a blood meal. In order to better understand the genes involved in preparing the females to take a blood meal, populations of non-blooded adult female Cx. more...

Organism:

Culex quinquefasciatus

Type:

Expression profiling by high throughput sequencing

Platform:

GPL14891

7 Samples

Download data: TXT

(Submitter supplied) High throughput sequencing was performed using Illumina HiSeq to identify differentially regulated genes in Culex mosquitoes after West Nile virus infection.

Organism:

Culex quinquefasciatus

Type:

Expression profiling by high throughput sequencing

Platform:

GPL14891

4 Samples

Download data: TXT

(Submitter supplied) Investigation of gene expression level differences in Culex pipiens (SB) and C. quinquefasciatus (JHB) at three time points (8, 16, and 24 hours post-exposure) during the early pupal state in standard (25°C; 16 h light/8 h dark) and diapause-inducing (18°C; 8 h light/16 h dark) conditions.

Organism:

Culex quinquefasciatus; Culex pipiens

Type:

Expression profiling by array

Platform:

GPL18562

48 Samples

Download data: PAIR

(Submitter supplied) Culex pipiens molestus and Cx. p. quinquefasciatus are the members of Culex pipiens Complex, but they display relatively large differences in behavior and physiological responses. We compared the genes of these mosquitoes to identify those that were differentially expressed in each subspecies. Such genes could play important roles in subspecies-specific blood feeding or oviposition behavior.

Organism:

Culex pipiens molestus; Culex quinquefasciatus

Type:

Expression profiling by high throughput sequencing

Platforms:

GPL14891 GPL18865

2 Samples

Download data: TXT

(Submitter supplied) Culex pipiens pallens and Cx. p. quinquefasciatus are important vectors of many diseases, such as West Nile fever and lymphatic filariasis. The widespread use of insecticides to control these disease vectors and other insect pests has led to insecticide resistance becoming common in these species. High throughput screening using SSH and specific microarray platforms was thought to have identified some resistance-related genes. more...

Organism:

Culex quinquefasciatus; Culex pipiens pallens

Type:

Expression profiling by high throughput sequencing

Platforms:

GPL14891 GPL18651

12 Samples

Download data: TXT

(Submitter supplied) The genomes of three major mosquito vectors of human diseases, including Anopheles gambiae, Aedes aegypti, and Culex pipiens quinquefasciatus, have been previously sequenced. C. p. quinquefasciatus has the largest number of predicted protein-coding genes, which partially results from the expansion of three detoxification gene families: cytochrome P450 monooxygenases (P450), glutathione S-transferases (GST), and carboxylcholinesterases (CCE). more...

Organism:

Culex quinquefasciatus

Type:

Expression profiling by high throughput sequencing

Platform:

GPL15222

5 Samples

Download data: TXT

(Submitter supplied) Illumina HiSeq 2000 was conducted on the mRNA fraction of fourth instar Cx. quinquefasciatus from a highly permethrin resistant strain (HAmCqG8) and its parental low resistance strain (HAmCqG0). After aligning reads to the Johannesburg genome using the GTF annotations file from Ensembl Metazoa, we found that 367 genes were upregulated in the high resistant strain and 3982 were downregulated. The upregulated genes were associated with cytochrome P450s and proteases while the downregulated genes were mostly found in the “no annotation” category for the Structural Classification of Proteins classifications for Cx. more...

Organism:

Culex quinquefasciatus

Type:

Expression profiling by high throughput sequencing

Platform:

GPL14891

2 Samples

Download data: TXT

(Submitter supplied) Analysis of Culex quinquefasciatus responses to West Nile virus (WNV) infection at 7 and 14 days after ingestion of infected blood in the gut and carcass tissues.

Organism:

Culex quinquefasciatus

Type:

Expression profiling by array

Platform:

GPL10712

16 Samples

Download data

(Submitter supplied) A pyrethroid-resistant strain of Culex quinquefasciatus, JPal-per, exhibits 2500-fold greater larval resistance to permethrin than the insecticide-susceptible strain Ogasawara. An increased microsome monooxygenase metabolism is involved in the resistance mechanism. Microarray analysis revealed altered expressions of cytochrome P450 genes in the fourth instar larvae of JPal-per compared to those in OGS. more...

Organism:

Culex quinquefasciatus

Type:

Expression profiling by array

Platform:

GPL8743

10 Samples

Download data: TXT