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Items: 3

1.

Gene expression profiles in mouse embryonic midbrain of Wnt1-lineage specific Gpr161 deletion.

(Submitter supplied) To explore the differentially expressed genes in embryonic midbrain development in Wnt1-lineage specific Gpr161 deleted mouse embryos.
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL21103
9 Samples
Download data: CSV
Series
Accession:
GSE185336
ID:
200185336
2.

Investigation of conventional and unconventional protein secretion using galectin-3

(Submitter supplied) Protein secretion is an essential process in cell biology. The conventional secretion pathway is well known, and involves proteins with a signal sequence being directed into the endoplasmic reticulum. Once in the lumen of the endoplasmic reticulum, proteins are trafficked through the Golgi and remain separate from the cytosol throughout their journey to the outside of the cell. More recently, proteins without a signal sequence have been found outside the cell. more...
Organism:
Homo sapiens
Type:
Other
Platform:
GPL20301
32 Samples
Download data: TXT, XLSX
Series
Accession:
GSE157864
ID:
200157864
3.

Genome-wide CRISPR screening identifies new regulators of glycoprotein secretion

(Submitter supplied) Background: The fundamental process of protein secretion from eukaryotic cells has been well described for many years, yet gaps in our understanding of how this process is regulated remain. Methods: With the aim of identifying novel genes involved in the secretion of glycoproteins, we used a screening pipeline consisting of a pooled genome-wide CRISPR screen, followed by secondary siRNA screening of the hits to identify and validate several novel regulators of protein secretion. more...
Organism:
Homo sapiens
Type:
Other
Platform:
GPL20301
60 Samples
Download data: XLSX
Series
Accession:
GSE133692
ID:
200133692
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