GSM896752[Accession] - GEO DataSets

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Items: 3

Select item 2000365491.

Expression correlates of the full-length androgen receptor and its splicing variants

(Submitter supplied) Continued androgen receptor (AR) signaling is an established mechanism underlying castration-resistant prostate cancer (CRPC), and suppression of AR signaling remains a therapeutic goal of CRPC therapy. Constitutively active androgen receptor splicing variants (AR-Vs) lack the AR ligand-binding domain (AR-LBD), the intended target of androgen deprivation therapies (ADT) including new CRPC therapies such as abiraterone and MDV3100. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL4133
14 Samples

Download data: TXT

Series

Accession:: GSE36549

ID:: 200036549

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 1000041332.

Agilent-014850 Whole Human Genome Microarray 4x44K G4112F (Feature Number version)

(Submitter supplied) This multi-pack (4X44K) formatted microarray represents a compiled view of the human genome as it is understood today. The sequence information used to design this product was derived from a broad survey of well known sources such as RefSeq, Goldenpath, Ensembl, Unigene and others. The resulting view of the human genome covers 41K unique genes and transcripts which have been verified and optimized by alignment to the human genome assembly and by Agilent's Empirical Validation process. more...

Organism:: Homo sapiens

10 DataSets
841 Series
3 Related Platforms
15456 Samples

Download data: TXT

Platform

Accession:: GPL4133

ID:: 100004133

Select item 3008967523.

LNCaP95_LBDsiRNA_R1881

Organism:: Homo sapiens

Source name:: LNCaP95 cells transfected with siRNA trageting AR-LBD and cultured in 1nM R1881 (channel 1) Total RNA from LNCaP cells grown in normal culture conditions (channel 2)