GEO DataSets

(Submitter supplied) Here we identify a novel class of small RNAs that are ~21-nucleotide in length and are produced from the sequences in the vicinity of DNA double strand break (DSB) sites in Arabidopsis and humans. We named them diRNAs for DSB-induced small RNAs. In Arabidopsis, the biogenesis of diRNAs requires the PI3 kinase ATR, RNA polymerase IV (Pol IV), and Dicer-like proteins. Mutations in these proteins as well as in Pol V cause significant reduction in DSB repair efficiency. more...

Organism:

Arabidopsis thaliana; Homo sapiens

Type:

Non-coding RNA profiling by high throughput sequencing

Platforms:

GPL9062 GPL11221 GPL10999

33 Samples

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