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Items: 3

1.

Differential responses to selective CDK2 inhibitor BLU-222 is conditioned by tumor suppressors

(Submitter supplied) The selective CDK2 inhibitor BLU-222 was evaluated for mechanisms of response in the context of ovarian and breast cancer models. Using sensors of cellular CDK activity, it was found that sensitivity to either CDK4/6 or CDK2 inhibition is related to the differential dependence on a single CDK for G1/S transition. Unlike CDK4/6 inhibitors, BLU-222 was able to robustly inhibit proliferation through cell cycle inhibition in both G1 and G2 phases. more...
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platform:
GPL11154
18 Samples
Download data: RESULTS
Series
Accession:
GSE281746
ID:
200281746

PubMed

2.

Illumina HiSeq 2000 (Homo sapiens)

Organism:
Homo sapiens
10740 Series
186906 Samples
Download data
Platform
Accession:
GPL11154
ID:
100011154

3.

Kuramochi, DMSO, rep 3

Organism:
Homo sapiens
Source name:
Kuramochi
Platform:
GPL11154
Series:
GSE281746
Download data: RESULTS
Sample
Accession:
GSM8627468
ID:
308627468

SRA Run Selector

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db=gds|term=GSM8627468[Accession]|query=1|qty=2|blobid=MCID_68567ccb0549615056ab6f02|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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