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Items: 3

1.

Ad-SGE-DKK3 Gene Therapy Against Resistance to Immune Checkpoint Blockade in Malignant Mesothelioma

(Submitter supplied) This phase 2 study evaluates the combination of Ad-SGE-Dickkopf-3 (DKK3) gene therapy and nivolumab in patients with chemotherapy-refractory epithelioid malignant pleural mesothelioma (MPM). This clinical study was based on our preclinical study to overcome primary immune resistance by combining Ad-SGE-DKK3 gene therapy with anti-PD-1 therapy through DKK3-driven immune modulation in mesothelioma. The study enrolled 12 patients between 2019 and 2022, who were refractory to pemetrexed-platin-based chemotherapy. more...
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL24247
6 Samples
Download data: RESULTS
Series
Accession:
GSE273448
ID:
200273448

2.

Illumina NovaSeq 6000 (Mus musculus)

Organism:
Mus musculus
16244 Series
723945 Samples
Download data
Platform
Accession:
GPL24247
ID:
100024247

3.

Control_01

Organism:
Mus musculus
Source name:
Tumor
Platform:
GPL24247
Series:
GSE273448
Download data: RESULTS
Sample
Accession:
GSM8428642
ID:
308428642

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db=gds|term=GSM8428642[Accession]|query=1|qty=2|blobid=MCID_67d6afb0e6bb2940138e1fee|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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