GEO DataSets

(Submitter supplied) Human lactoferrin (LF) is a multifunctional protein involved in immunomodulation, cell growth, and differentiation. In addition to the secreted form (sLF), an alternatively spliced form (ΔLF) that lacks the signal sequence and downregulated in cancer was found. This study was carried out to identify and compare signaling networks provoked by the two LF isoforms. To do this, the two forms were overexpressed in HEK293 cells using the flp-in/tet-on system and genome-wide expression analysis of 18,367 genes was conducted.

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL6254

2 Samples

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(Submitter supplied) Phalanx Biotech Group's Human OneArray contains 32,048 features, 30968 detection probes and 1080 control probes, spotted onto glass slides using a proprietary non-contact printing method. Detection probes are annotated against the human genome and grouped into the following categories: Group 1 - gene specific: exon Group 2 - intron hit Group 3 - intergenic Group 4 - multi-gene hits Group 5 - no hit to genome Group 6 - >200 hits to genome Protocol: See http://www.phalanxbiotech.com/ for updated protocols

Organism:

Homo sapiens

41 Series

2 Related Platforms

653 Samples

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