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Items: 4

1.

RNASeq, multiome, and genomic profiling of hematopoietic progenitors and B cells from mice with a point mutation in MYC [Multiome]

(Submitter supplied) We generated mice with a mutation at threonine 58 of MYC in the mouse germline (T58A mutant). These mice ultimately develop AML or B cell lymphomas. We profiled changes in gene expression and genomic occupation of MYC in single cells of sorted, immature bone marrow progenitor cells, mature (spleen derived) and immature (marrow derived) B cells. B cells were stimulated with LPS and IL7, respectively.
Organism:
Mus musculus
Type:
Other
Platform:
GPL30172
8 Samples
Download data: TSV
Series
Accession:
GSE247756
ID:
200247756
2.

A Germline Point Mutation in the MYC-FBW7 Phosphodegron Results in a Tumor-Prone Phenotype

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing; Other; Genome binding/occupancy profiling by high throughput sequencing
Platforms:
GPL17021 GPL30172
58 Samples
Download data: BW
Series
Accession:
GSE247757
ID:
200247757
3.

NextSeq 2000 (Mus musculus)

Platform
Accession:
GPL30172
ID:
100030172
4.

Single cell multiome 10x from lineage-Sca1+ckit+ sorted marrow WT cells replicate 2 ATAC

Organism:
Mus musculus
Source name:
Lin-Scai+ckit+ marrow Cells
Platform:
GPL30172
Series:
GSE247756 GSE247757
Download data
Sample
Accession:
GSM7900396
ID:
307900396
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Supplemental Content

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