GSM7832134[Accession] - GEO DataSets

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Items: 4

Select item 2002449291.

Active regulatory elements recruit cohesin to establish cell-specific chromatin domains.

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Mus musculus; Homo sapiens

Type:: Genome binding/occupancy profiling by high throughput sequencing; Other; Expression profiling by high throughput sequencing

Platforms:: GPL19057 GPL18573
44 Samples

Download data: BIGWIG, BW

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Accession:: GSE244929

ID:: 200244929

PubMed

Select item 2002449252.

Active regulatory elements recruit cohesin to establish cell-specific chromatin domains [ChIP-seq]

(Submitter supplied) The genome adopts varied and specific 3D conformations in different cell types. The loop extruding factor, cohesin, is thought to play a key role in the formation of this 3D structure, however it is unknown how cell-type specificity is achieved. One proposed mechanism is that cis-regulatory elements, which are active in unique combinations in different cell types, recruit cohesin and therefore direct the formation of specific 3D conformation. more...