GSM7828292[Accession] - GEO DataSets

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Items: 4

Select item 2002447431.

Lymph Node Stromal Cell Responses to Perinatal T Cell Waves, A Temporal Atlas

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Mus musculus

Type:: Expression profiling by high throughput sequencing

Platforms:: GPL19057 GPL21273
28 Samples

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Series

Accession:: GSE244743

ID:: 200244743

PubMed Full text in PMC Similar studies

Select item 2002447412.

Lymph Node Stromal Cell Responses to Perinatal T Cell Waves, A Temporal Atlas [bulkRNA-Seq]

(Submitter supplied) The perinatal period is a critical time-window in establishing T-cell tolerance. Regulatory T cells (Tregs) made during the first two weeks of life are key drivers of perinatal tolerance induction, but how these cells are generated and operate has not been established. To elucidate the unique environment murine perinatal Tregs encounter within the lymph nodes (LNs) as they first emerge from the thymus, and how it evolves over the succeeding days, we employed single-cell RNA sequencing to generate an atlas of the early LN niche. more...