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Items: 3

1.

Circular RNA vectors encapsulated in lipid nanoparticles for sustained protein replacement therapy in the retina

(Submitter supplied) Circular RNAs (circRNAs) have recently emerged as promising vectors for sustained therapeutic protein production due to their enhanced stability from exonuclease degradation. Here, we engineered circRNAs expressing reporters and neurotrophic factors, and systematically compared their expression kinetics to conventional linear mRNAs. CircRNAs achieved 10-20 fold higher and more persistent protein expression in vitro over several weeks. more...
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL24247
6 Samples
Download data: TAR
Series
Accession:
GSE243992
ID:
200243992

PubMed Full text in PMC Similar studies

2.

Illumina NovaSeq 6000 (Mus musculus)

Organism:
Mus musculus
19809 Series
775891 Samples
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Platform
Accession:
GPL24247
ID:
100024247

3.

CTR1,scRNAseq

Organism:
Mus musculus
Source name:
retina
Platform:
GPL24247
Series:
GSE243992
Download data: TAR
Sample
Accession:
GSM7802906
ID:
307802906

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db=gds|term=GSM7802906[Accession]|query=1|qty=2|blobid=MCID_691d89a299c3d775c6a835eb|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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