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Items: 4

1.

Mechanism for controlled assembly of transcriptional condensates by Aire

(Submitter supplied) Transcriptional condensates play a crucial role in gene expression and regulation, yet their assembly mechanisms remain poorly understood. We here report a multi-layered mechanism for condensate assembly by Autoimmune regulator (Aire), an essential transcriptional regulator (TR) that orchestrates gene expression reprogramming for central T-cell tolerance. Aire condensates assemble on enhancers, stimulating local transcriptional activities and connecting disparate inter-chromosomal loci. more...
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing; Other; Genome binding/occupancy profiling by high throughput sequencing
Platforms:
GPL34281 GPL20301 GPL24676
75 Samples
Download data: BW
Series
Accession:
GSE243825
ID:
200243825

PubMed

2.

Mechanism for controlled assembly of transcriptional condensates by Aire [ChIP-seq]

(Submitter supplied) Transcriptional condensates play a crucial role in gene expression and regulation, yet their assembly mechanisms remain poorly understood. We here report a multi-layered mechanism for condensate assembly by Autoimmune regulator (Aire), an essential transcriptional regulator (TR) that orchestrates gene expression reprogramming for central T-cell tolerance. Aire condensates assemble on enhancers, stimulating local transcriptional activities and connecting disparate inter-chromosomal loci. more...
Organism:
Homo sapiens
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platforms:
GPL24676 GPL34281
46 Samples
Download data: BW
Series
Accession:
GSE243824
ID:
200243824

PubMed

3.

Illumina NovaSeq 6000 (Homo sapiens)

Organism:
Homo sapiens
20134 Series
990487 Samples
Download data
Platform
Accession:
GPL24676
ID:
100024676

4.

H3K27ac, no Dox, rep1

Organism:
Homo sapiens
Source name:
4D6
Platform:
GPL24676
Series:
GSE243824 GSE243825
Download data: BW
Sample
Accession:
GSM7796160
ID:
307796160

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db=gds|term=GSM7796160[Accession]|query=1|qty=2|blobid=MCID_682acd6f8d11fb4548ced1b5|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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