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Items: 4

1.

Cytosolic PRRs are required to upregulate interferon gene expression upon EZH2 inhibition with GSK343 in B16-F10 melanoma cells [RNA-seq]

(Submitter supplied) EZH2 is a histone methyltransferase that deposits the repressive histone H3 lysine 27 trimethylation (H3K27me3). This mark has been reported to silence expression of various repetitive elements in the genome. We sought to identify the effect of EZH2 inhibition on coding and non-coding, repetitive RNA expression. We generated a novel mutant mouse line whose ability to detect induced repeat element expression has been abrogated. more...
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL19057
24 Samples
Download data: CSV, TXT
Series
Accession:
GSE239879
ID:
200239879
2.

Cytosolic pattern recognition receptors respond to EZH2-inhibition induced viral mimicry response that eliminates splenic B cells

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing; Methylation profiling by array
Platforms:
GPL30650 GPL19057
70 Samples
Download data: BW, CSV, IDAT, TXT
Series
Accession:
GSE198232
ID:
200198232
3.

Illumina NextSeq 500 (Mus musculus)

Platform
Accession:
GPL19057
ID:
100019057
4.

RIG DMSO Rep3

Organism:
Mus musculus
Source name:
B16-F10 melanoma cells
Platform:
GPL19057
Series:
GSE198232 GSE239879
Download data: CSV, TXT
Sample
Accession:
GSM7676092
ID:
307676092
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