GSM7512424[Accession] - GEO DataSets

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Items: 4

Select item 2002359681.

A non-canonical repressor function of JUN restrains YAP activity and suppresses YAP-dependent liver cancer growth

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Homo sapiens

Type:: Expression profiling by high throughput sequencing; Other

Platforms:: GPL18573 GPL24676
178 Samples

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Series

Accession:: GSE235968

ID:: 200235968

PubMed

Select item 2002359632.

A non-canonical repressor function of JUN restrains YAP activity and suppresses YAP-dependent liver cancer growth [CutRun_in_constitutive_5SA_MCF10A]

(Submitter supplied) The transcriptional coactivators YAP/TAZ are the critical downstream regulators of the Hippo pathway that regulate gene expression in response to changes in pathway activity, mainly by binding to TEAD transcription factors. Uncontrolled transcriptional output of YAP/TAZ can lead to rapid induction of aggressive tumor growth. AP-1 is a dimeric basic leucine zipper (bZIP) transcription factor complex with JUN and FOS proteins being the most abundant members of this family. more...