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Items: 4

1.

Epigenetic and transcriptomic alterations in key inflammatory pathways are established in RUNX1 deficient hematopoietic progenitors and are propagated to neutrophils [HI-C]

(Submitter supplied) Epigenome and transcriptome characterization of RUNX1 deficient hematopoietic cells. We hypothesized that epigenetic alterations in key inflammatory pathway genes are acquired in RUNX1 deficient granulocyte-monocyte progenitors (GMPs) and are propagated to neutrophils. We deleted RUNX1 using Cebpa-Cre, which deletes primarily in GMPs. We analyzed the basal transcriptional changes caused by the loss of RUNX1 in purified GMPs and neutrophils by bulk RNA-seq. more...
Organism:
Mus musculus
Type:
Other
Platform:
GPL24247
8 Samples
Download data: BED, MATRIX
Series
Accession:
GSE234847
ID:
200234847
2.

Epigenetic and transcriptomic alterations in key inflammatory pathways are established in RUNX1 deficient hematopoietic progenitors and are propagated to neutrophils.

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Mus musculus; Homo sapiens
Type:
Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by high throughput sequencing; Other
Platforms:
GPL24247 GPL16791 GPL17021
55 Samples
Download data: BED, BW, MATRIX
Series
Accession:
GSE221427
ID:
200221427
3.

Illumina NovaSeq 6000 (Mus musculus)

Platform
Accession:
GPL24247
ID:
100024247
4.

GMP_WT_A_HIC

Organism:
Mus musculus
Source name:
BM GMPs
Platform:
GPL24247
Series:
GSE221427 GSE234847
Download data: MATRIX
Sample
Accession:
GSM7475844
ID:
307475844
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Supplemental Content

db=gds|term=GSM7475844[Accession]|query=1|qty=3|blobid=MCID_67d5435673a8307cd8a25c78|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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