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Items: 3

1.

Human Smc5/6 recognizes transcription-generated positive DNA supercoils

(Submitter supplied) Beyond its essential roles in ensuring faithful chromosome segregation and genomic stability, the human Smc5/6 complex acts as an antiviral factor. It binds to and impedes the transcription of extrachromosomal DNA templates; an ability which is lost upon chromosomal DNA integration. How the complex distinguishes among different DNA templates is unknown. Here we show that, in human cells, Smc5/6 preferentially binds to circular rather than linear extrachromosomal DNA. more...
Organism:
Homo sapiens
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platforms:
GPL24676 GPL20301
9 Samples
Download data: BED
Series
Accession:
GSE231328
ID:
200231328

PubMed

2.

Illumina NovaSeq 6000 (Homo sapiens)

Organism:
Homo sapiens
21048 Series
1008685 Samples
Download data
Platform
Accession:
GPL24676
ID:
100024676

3.

ChIP-Seq_HA-Smc6_hTERT-RPE1_TPT

Organism:
Homo sapiens
Source name:
hTERT-RPE1
Platform:
GPL24676
Series:
GSE231328
Download data: BED
Sample
Accession:
GSM7265145
ID:
307265145

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db=gds|term=GSM7265145[Accession]|query=1|qty=2|blobid=MCID_68746fb9d8bfb71a7ad06322|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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