GSM6956519[Accession] - GEO DataSets - NCBI

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Items: 4

Select item 2002234541.

Combinatorial effects on gene expression at the Lbx1/Fgf8 locus resolve Split-Hand/Foot Malformation type 3 [4C-seq]

(Submitter supplied) Split-Hand/Foot Malformation type 3 (SHFM3) is a congenital limb malformation associated with tandem duplications at the LBX1/FGF8 locus. Yet, the disease patho-mechanism remains unsolved. Here we investigated the functional consequences of SHFM3-associated rearrangements on chromatin conformation and gene expression in vivo in transgenic mice. We show that the Lbx1/Fgf8 locus consists of two separate, but interacting, regulatory domains. more...

Organism:: Homo sapiens

Type:: Other

Platform:: GPL24676
12 Samples

Download data: BEDGRAPH, WIG

Series

Accession:: GSE223454

ID:: 200223454

PubMed Full text in PMC Similar studies

Select item 2001974042.

Combinatorial effects on gene expression at the Lbx1/Fgf8 locus resolve Split-Hand/Foot Malformation type 3

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Mus musculus; Homo sapiens

Type:: Other; Expression profiling by high throughput sequencing

4 related Platforms
44 Samples

Download data: BEDGRAPH, WIG

Series

Accession:: GSE197404

ID:: 200197404

PubMed Full text in PMC Similar studies

Select item 1000246763.

Illumina NovaSeq 6000 (Homo sapiens)

Organism:: Homo sapiens

22812 Series
1047101 Samples

Platform

Accession:: GPL24676

ID:: 100024676

Select item 3069565194.

4Cseq-hg-Control-FB-FGF8-Rep1-L21103

Organism:: Homo sapiens

Source name:: Skin fibroblasts

Platform:: GPL24676
Series:: GSE197404 GSE223454

Download data: BEDGRAPH, WIG

Sample

Accession:: GSM6956519

ID:: 306956519

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