GSM686632[Accession] - GEO DataSets

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Items: 3

Select item 2000277841.

Transcriptional profiling of ATP-competitive mTOR inhibitors reveals mTORC1 and mTORC2 specific regulatory networks

(Submitter supplied) The mammalian target of rapamycin (mTOR) is a central regulator of cell growth and proliferation in response to growth factor and nutrient signaling. Consequently, this kinase is implicated in metabolic diseases including cancer and diabetes so there is great interest in understanding mTOR regulatory networks. mTOR exists in two functionally distinct complexes, mTORC1 and mTORC2, and whereas the natural product rapamycin only inhibits a subset of mTORC1 functions, recently developed ATP-competitive mTOR inhibitors have revealed new roles for both complexes. more...

Organism:: Mus musculus

Type:: Expression profiling by array

Platform:: GPL7202
12 Samples

Download data: TXT

Series

Accession:: GSE27784

ID:: 200027784

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 1000072022.

Agilent-014868 Whole Mouse Genome Microarray 4x44K G4122F (Probe Name version)

(Submitter supplied) Designed to truly represent all known genes in the mouse genome and their resulting transcripts, Agilent's Whole Mouse Genome Oligo – 4X44K microarray is comprised of 41,534 60-mer oligonucleotide probes representing over 41,000 mouse genes and transcripts. Content for this microarray was generated from leading public databases, including RefSeq, RIKEN, NIA, Ensembl, RIKEN, UCSC Goldenpath, and Unigene. more...