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Items: 4

1.

SETD1A regulates transcriptional pause release of heme biosynthesis genes in leukemia

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platforms:
GPL18573 GPL24676 GPL18460
73 Samples
Download data: BIGWIG
Series
Accession:
GSE189894
ID:
200189894
2.

SETD1A regulates transcriptional pause release of heme biosynthesis genes in leukemia [RNA-seq]

(Submitter supplied) Histone methyltransferase SETD1A is critical for acute myeloid leukemia (AML) cell survival, but the molecular mechanism driving SETD1A gene regulation remains elusive. To delineate the role of SETD1A, we utilize a protein degrader technology to induce rapid SETD1A degradation in AML cell lines. SETD1A degradation results in immediate downregulation of transcripts associated with DNA repair and heme biosynthesis pathways. more...
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platform:
GPL18573
23 Samples
Download data: BIGWIG, XLSX
Series
Accession:
GSE189893
ID:
200189893
3.

Illumina NextSeq 500 (Homo sapiens)

Platform
Accession:
GPL18573
ID:
100018573
4.

SETD1AKO_FKBP-SETD1A_DMSO_1h_EU_30min

Organism:
Homo sapiens
Source name:
MOLM-13
Platform:
GPL18573
Series:
GSE189893 GSE189894
Download data: BIGWIG
Sample
Accession:
GSM6443257
ID:
306443257
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Supplemental Content

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