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Items: 4

1.

A network of DZF proteins controls alternative splicing regulation and fidelity.

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below. GSE206058: Paired-end total RNA-seq of triplicate biological replicate treatments of HEK-293 cells with negative control siRNAs or siRNAs targeting ZFR, ILF2, or ILF3. GSE206059: eCLIP analysis of FLAG-ZFR binding in HEK-293 Flp-In TREx cell lines, with size-matched input control. GSE206060: RNA Bind-n-Seq of recombinantly expressed and purified ZFR-ILF2 complexes, with PTBP1 as a positive control for successful library generation.
Organism:
synthetic construct; Homo sapiens
Type:
Expression profiling by high throughput sequencing; Other
Platforms:
GPL21290 GPL27484
28 Samples
Download data: BED
Series
Accession:
GSE206061
ID:
200206061
2.

A network of DZF proteins controls alternative splicing regulation and fidelity [eCLIP-seq]

(Submitter supplied) Proteins containing DZF (domain associated with zinc fingers) modules play important roles throughout gene expression, from transcription to translation. Derived from nucleotidyltransferases but lacking catalytic residues, DZF domains serve as heterodimerization surfaces between DZF protein pairs. Three DZF proteins are widely expressed in mammalian tissues, ILF2, ILF3, and ZFR, which form mutually exclusive ILF2-ILF3 and ILF2-ZFR heterodimers. more...
Organism:
Homo sapiens
Type:
Other
Platform:
GPL21290
4 Samples
Download data: BED
Series
Accession:
GSE206059
ID:
200206059
3.

Illumina HiSeq 3000 (Homo sapiens)

Platform
Accession:
GPL21290
ID:
100021290
4.

ZFR-eCLIP-2

Organism:
Homo sapiens
Source name:
HEK-293 Flp-In TREx cells
Platform:
GPL21290
Series:
GSE206059 GSE206061
Download data: BED
Sample
Accession:
GSM6241093
ID:
306241093
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