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Items: 4

1.

Chromatin opening by p53 is confined by Trim24 in a histone methylation-dependent manner [ChIP-seq]

(Submitter supplied) Chromatin modifications are thought to provide additional context dependence for sequence-based gene activation. Binding sites of the transcription factor (TF) and important tumor suppressor p53 are unusually diverse with regards to their chromatin accessibility and histone modifications, suggesting different modes of binding. Here, we show that the ability of p53 to open chromatin and activate its target genes upon DNA damage is locally restricted by its cofactor Trim24. more...
Organism:
Mus musculus; Homo sapiens
Type:
Genome binding/occupancy profiling by high throughput sequencing
4 related Platforms
67 Samples
Download data: BW, WIG
Series
Accession:
GSE200580
ID:
200200580
2.

Chromatin opening by p53 is confined by Trim24 in a histone methylation-dependent manner

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Homo sapiens; Mus musculus
Type:
Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by high throughput sequencing
4 related Platforms
174 Samples
Download data: BW, WIG
Series
Accession:
GSE200586
ID:
200200586
3.

Illumina HiSeq 2500 (Mus musculus)

Platform
Accession:
GPL17021
ID:
100017021
4.

ChIPseq_ESC_wt_p53_Unt_r2

Organism:
Mus musculus
Source name:
embryonic stem cells
Platform:
GPL17021
Series:
GSE200580 GSE200586
Download data: WIG
Sample
Accession:
GSM6038036
ID:
306038036
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