GSM5956545[Accession] - GEO DataSets

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Items: 4

Select item 2001987781.

The leukocyte NADPH oxidase 2 (NOX2) plays a key role in pathogen killing and immunoregulation

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Mus musculus

Type:: Expression profiling by array; Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing

Platforms:: GPL11202 GPL21493
42 Samples

Download data: TXT

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Accession:: GSE198778

ID:: 200198778

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2001987692.

Bronchoalveolar lavage alveolar macrophage subset transcriptomes in WT and NOX2-knockout mice

(Submitter supplied) The leukocyte NADPH oxidase 2 (NOX2) plays a key role in pathogen killing and immunoregulation. Genetic defects in NOX2 result in chronic granulomatous disease (CGD), associated with microbial infections and inflammatory disorders, often involving the lung. Alveolar macrophages (AM) are the predominant immune cell in the airways at steady state, and limiting their activation is important given constant exposure to inhaled materials, yet the importance of NOX2 in this process is not well-understood. more...