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Items: 4

1.

Pausing of RNA polymerase II disrupts DNA-specified nucleosome organization to enable precise gene regulation

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Drosophila melanogaster
Type:
Genome binding/occupancy profiling by genome tiling array; Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by array
Platforms:
GPL1322 GPL9061 GPL6888
30 Samples
Download data: CEL, CHP, PAIR
Series
Accession:
GSE20472
ID:
200020472
2.

Pausing of RNA polymerase II disrupts DNA-specified nucleosome organization to enable precise gene regulation: ChIP-chip data

(Submitter supplied) Metazoan transcription is controlled through either coordinated recruitment of transcription machinery to the gene promoter, or subsequently, through regulated pausing of RNA polymerase II (Pol II) in early elongation. We report that a key difference between genes that use these distinct regulatory strategies lies in the chromatin architecture specified by their DNA sequences. Pol II pausing is prominent at highly-regulated genes whose sequences inherently disfavor nucleosome formation within the gene, but favor nucleosomal occlusion of the promoter. more...
Organism:
Drosophila melanogaster
Type:
Genome binding/occupancy profiling by genome tiling array
Platform:
GPL6888
21 Samples
Download data: PAIR, TXT
Series
Accession:
GSE20471
ID:
200020471
3.

Henikoff_Dmel_r52_ChIP tiling design

(Submitter supplied) Tiling array using NimbleGen platform (DesignID=6473/6474/6475). FlyBase release 5.2. Complete tiling of Dmel FBr5 pseudo-chromosomes; no filtering; isothermal (target tm=76); mean probe length=53 (range=50 to 75); mean distance between probes=12; every other probe reversed. Protocol: http://www.nimblegen.com/products/chip/index.html
Organism:
Drosophila melanogaster
26 Series
129 Samples
Download data: GFF, NDF
Platform
Accession:
GPL6888
ID:
100006888
4.

Pol_II_(-)Ecdysone_2_Adelman

Organism:
Drosophila melanogaster
Source name:
Drosophila S2 cells (Invitrogen), Pol II (Rpb3) IP DNA (channel 1) Drosophila S2 cells (Invitrogen), Input DNA (channel 2)
Platform:
GPL6888
Series:
GSE20471 GSE20472
Download data: PAIR
Sample
Accession:
GSM594181
ID:
300594181
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Supplemental Content

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