GSM5747748[Accession] - GEO DataSets

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Items: 4

Select item 2001924861.

Identification of TBX3 and shared HAND2-TBX3 target genes in early mouse limb buds

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Mus musculus

Type:: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing

Platform:: GPL19057
16 Samples

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Accession:: GSE192486

ID:: 200192486

Select item 2001924842.

Identification of TBX3 and shared HAND2-TBX3 target genes in early mouse limb buds [ChIP-seq]

(Submitter supplied) ChIP-seq is combined with RNA-seq analysis to identify the TBX3 and HAND2 target genes during mouse limb bud development. This analysis identifies the DEGs and direct transcriptional targets of HAND2 and TBX3 during the early determinative period critical to establishment of limb axis polarity and the SHH signaling center in the posterior limb bud mesenchyme. In particular, bioinformatics analysis identifies the target gene networks that are co-regulated by both TBX3 and HAND2 transcription factors in the limb bud mesenchyme. more...