GSM533577[Accession] - GEO DataSets

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Items: 3

Select item 2000213521.

Azole Resistance Mechanism in Candida glabrata Oropharyngeal Isolates

(Submitter supplied) Microarray was used to analyze azole resistance of Candida glabrata oropharyngeal isolates from 7 hematopoietic stem cell transplant recipients receiving fluconazole prophylaxis. Transcriptional profiling of the sequential-paired clinical isolates by microarray revealed 19 genes upregulated in the majority of resistant isolates compared to their paired-susceptible isolates. All seven resistant isolates had greater than two fold upregulation of CgPDR1, a master transcriptional regulator of PDR network, and all 7 resistant isolates showed upregulation of known CgPDR1-target genes. more...

Organism:: Nakaseomyces glabratus

Type:: Expression profiling by array

Platform:: GPL8174
35 Samples

Download data: GPR

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Accession:: GSE21352

ID:: 200021352

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 1000081742.

NIAID Cgaa -- Candida glabrata 6K

(Submitter supplied) Microarrays were printed with an Omnigrid robotic arrayer by Genomic Solutions ( http://www.genomicsolutions.com ) that is fitted with a printhead and 32 SMP3 print tips from Telechem ( http://www.arrayit.com ). Candida glabrata expression oligonucleotide probes were purchased from Institut Pasteur. An additional 384 well plate containing control oligos was also included. Oligonucleotide probes in 384-well polypropylene plates (Genetix, 384 micro array) were dissolved in print buffer (150mM sodium phosphate, pH 8.5, 4% sodium sulfate, 0.0001% N-lauryl sarcosyl) to a normalized 25 micromolar concentration. more...