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Items: 3

1.

GATA Switch Enhancers Mark Dynamically Regulated Chromatin Interaction Nodes during Erythroid Maturation

(Submitter supplied) Erythropoiesis is among the best understood examples of cell differentiation. In a required step, GATA1 replaces GATA2 at genomic loci, termed GATA switch enhancers. Little is known about how this switch affects chromatin architecture. Here, we show that cohesin binds GATA1 and occupies most GATA switch enhancers. Cohesin-based chromatin interaction analysis demonstrated that the most dynamic and interactive enhancers are enriched for GATA switch sites/TAL1 occupancy and frequently lack super-enhancer features. more...
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing; Other; Genome binding/occupancy profiling by high throughput sequencing
Platforms:
GPL13112 GPL19057
18 Samples
Download data: BED, CSV, TXT
Series
Accession:
GSE155103
ID:
200155103
2.

Illumina HiSeq 2000 (Mus musculus)

Platform
Accession:
GPL13112
ID:
100013112
3.

G1E-ER4 0h - rnaseq_rep1

Organism:
Mus musculus
Source name:
G1E-ER4
Platform:
GPL13112
Series:
GSE155103
Download data
Sample
Accession:
GSM4695486
ID:
304695486
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Supplemental Content

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