GSM4608939[Accession] - GEO DataSets - NCBI

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Items: 4

Select item 2001521981.

IRF5 promotes intestinal inflammation by guiding monocyte differentiation towards pathogenic CD11c+ macrophage phenotype [scrnaseq_steady_state]

(Submitter supplied) Mononuclear phagocytes (MNPs) play a key role in maintaining intestinal homeostasis but also in triggering immunopathology in response to acute microbial stimulation, which induces the recruitment of masses of Ly6Chi monocytes to the gut. The regulators that control monocyte tissue adaptation in the gut remain poorly understood. Interferon Regulatory Factor 5 (IRF5) is a transcription factor previously shown to play a key role in maintaining the inflammatory phenotype of macrophages Here we investigate the impact of IRF5 on the MNP system and physiology of the gut at homeostasis and during inflammation. more...

Organism:: Mus musculus

Type:: Expression profiling by high throughput sequencing

Platform:: GPL24247
4 Samples

Download data: MTX, TSV

Series

Accession:: GSE152198

ID:: 200152198

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 2001292582.

IRF5 promotes intestinal inflammation by guiding monocyte differentiation towards pathogenic CD11c+ macrophage phenotype

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Mus musculus

Type:: Expression profiling by high throughput sequencing

Platforms:: GPL21103 GPL24247
24 Samples

Series

Accession:: GSE129258

ID:: 200129258

PubMed Full text in PMC Similar studies

Select item 1000242473.

Illumina NovaSeq 6000 (Mus musculus)

Organism:: Mus musculus

16352 Series
725772 Samples

Platform

Accession:: GPL24247

ID:: 100024247

Select item 3046089394.

pbmc_mono_wt_ss

Organism:: Mus musculus

Source name:: preipheral blood

Platform:: GPL24247
Series:: GSE129258 GSE152198

Sample

Accession:: GSM4608939

ID:: 304608939

SRA Run Selector

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GSM4608939[Accession] (4)
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