GSM4476693[Accession] - GEO DataSets

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Items: 4

Select item 2001486871.

A mechanism for microRNA arm switching regulated by uridylation

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Homo sapiens; Mus musculus

Type:: Expression profiling by high throughput sequencing; Non-coding RNA profiling by high throughput sequencing

Platforms:: GPL16417 GPL23227
21 Samples

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Series

Accession:: GSE148687

ID:: 200148687

PubMed Similar studies

Select item 2001486862.

A mechanism for microRNA arm switching regulated by uridylation [AQ-seq]

(Submitter supplied) Strand selection is a critical step in microRNA (miRNA) biogenesis. Although the dominant strand may alter depending on cellular contexts, the molecular mechanism and physiological significance of such alternative strand selection (or “arm switching”) remain elusive. Here we find miR-324 as one of the strongly regulated miRNAs by arm switching, and identify terminal uridylyl transferases TUT4 and TUT7 as the key regulators. more...