GSM4446327[Accession] - GEO DataSets

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Items: 4

Select item 2001477981.

BCL11A promotes myeloid leukemogenesis by abrogating the transcriptional activity of PU.1

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Mus musculus

Type:: Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by array

Platforms:: GPL11180 GPL16417
16 Samples

Download data: CEL, TDF

Series

Accession:: GSE147798

ID:: 200147798

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2001477972.

BCL11A promotes myeloid leukemogenesis by abrogating the transcriptional activity of PU.1 [array]

(Submitter supplied) The transcriptional repressor Bcl11a is involved in hematological malignancies, B-cell development and fetal to adult hemoglobin switching, however, the molecular mechanism how Bcl11a promotes development of myeloid leukemia remains largely unknown. We found that Bcl11a cooperates with the pseudokinase Trib1 in AML development. Bcl11a promotes proliferation of Trib1-expressing AML cells both in vitro and in vivo. more...

Organism:: Mus musculus

Type:: Expression profiling by array

Platform:: GPL11180
12 Samples

Download data: CEL

Series

Accession:: GSE147797

ID:: 200147797

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 1000111803.

[HT_MG-430_PM] Affymetrix HT MG-430 PM Array Plate

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html Protocol: see manufacturer's web site