GSM4225695[Accession] - GEO DataSets - NCBI

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Items: 4

Select item 2001423411.

Mouse models of neutropenia reveal progenitor-stage-specific defects [CITE-Seq]

(Submitter supplied) Advances in genetics and sequencing have lead to a deluge of disease-associated and disease-causing genetic alterations. Resolving causality between genetics and disease requires generating accurate models for molecular dissection; however, the rapid expansion of single-cell landscapes presents a major challenge to accurate comparisons between mutants and their wild type equivalents. Here, we generated mouse models of human severe congenital neutropenia (SCN) using patient-derived mutations in the Growth factor independent-1 (GFI1) transcription factor. more...

Organism:: Mus musculus

Type:: Expression profiling by high throughput sequencing

Platform:: GPL21103
14 Samples

Download data: H5, TXT

Series

Accession:: GSE142341

ID:: 200142341

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 2001204092.

A neutropenia-associated transcription factor mutation differentially impacts target genes in the cell-states traversed during granulocyte specification and commitment

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Homo sapiens; Mus musculus

Type:: Expression profiling by high throughput sequencing; Other

4 related Platforms
833 Samples

Download data: BED, H5, TXT

Series

Accession:: GSE120409

ID:: 200120409

PubMed Full text in PMC Similar studies

Select item 1000211033.

Illumina HiSeq 4000 (Mus musculus)

Organism:: Mus musculus

7203 Series
155364 Samples

Platform

Accession:: GPL21103

ID:: 100021103

Select item 3042256954.

Gfi1-K403R 10x CITE-Seq_ADT

Organism:: Mus musculus

Source name:: Bone marrow

Platform:: GPL21103
Series:: GSE120409 GSE142341

Sample

Accession:: GSM4225695

ID:: 304225695

SRA Run Selector

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