GSM4192696[Accession] - GEO DataSets

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Items: 4

Select item 2001410321.

Smooth muscle cell reprogramming in aortic aneurysms

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Homo sapiens; Mus musculus

Type:: Expression profiling by high throughput sequencing

Platforms:: GPL18573 GPL21273
32 Samples

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Accession:: GSE141032

ID:: 200141032

PubMed Full text in PMC Similar studies

Select item 2001410312.

Smooth muscle cell reprogramming in aortic aneurysms [scRNA-Seq]

(Submitter supplied) Smooth muscle cell TGFβ signaling is one of the primary drivers of smooth muscle cell maturation. Inhibition of smooth muscle cell TGFβ signaling in hyperlipidemic mice induces vessel wall inflammation and vessel wall dilation/dissection and leads aortic aneurysm. We performed scRNAseq method to examine smooth muscle cell gene expression profile using Apoe and SMC specific TGFbR2 KO in Apoe background mice.