GSM4006662[Accession] - GEO DataSets

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Items: 4

Select item 2001353411.

Enhancer RNAs mediate estrogen-induced decommissioning of selective enhancers by recruiting ER and its cofactor

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Homo sapiens

Type:: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing

Platform:: GPL21290
24 Samples

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Series

Accession:: GSE135341

ID:: 200135341

PubMed Full text in PMC Similar studies

Select item 2001353392.

Enhancer RNA mediate estrogen-induced transcriptional repression by recruiting ERa and its cofactor to selective enhancers [RNA-Seq]

(Submitter supplied) Estrogen receptor alpha (ERα) signaling mainly occupies on distal enhancers within genome and plays an essential role in ERα-positive breast cancer. ERα usually requires co-factors to regulate the enhancer activity. By analysis of genome-wide nascent transcript profiling in breast cancer cells, we identified a special group of eRNAs that are functionally important for estrogen-induced transcriptional repression. more...