GSM3963903[Accession] - GEO DataSets

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Items: 4

Select item 2001347071.

Cross-species analysis across 450 million years of evolution reveals conservation and divergence of the microglia program

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Ovis aries; Rattus norvegicus; Nannospalax galili; Gallus gallus; Macaca fascicularis; Mesocricetus auratus; Mus musculus; Danio rerio; Callithrix jacchus; Homo sapiens

Type:: Expression profiling by high throughput sequencing

10 related Platforms
81 Samples

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Series

Accession:: GSE134707

ID:: 200134707

PubMed Similar studies

Select item 2001347052.

Cross-species analysis across 450 million years of evolution reveals conservation and divergence of the microglia program (scRNA-seq)

(Submitter supplied) Here we characterize microglia transcriptional program across ten species spanning more than 450 million years of evolution. We find that microglia express a conserved core gene program of orthologous genes from rodents to human, including ligands and receptors associated with interactions between glia and neurons. In most species, microglia show a single dominant transcriptional state, while humans express significant microglia heterogeneity. more...

Organism:: Macaca fascicularis; Ovis aries; Rattus norvegicus; Homo sapiens; Mus musculus; Nannospalax galili; Danio rerio; Gallus gallus; Callithrix jacchus; Mesocricetus auratus