GSM3831314[Accession] - GEO DataSets - NCBI

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Items: 3

Select item 2001319411.

Myc is required for adaptive beta cell replication in young mice but is not sufficient in one year old mice fed with a high fat

(Submitter supplied) Purpose: To test the role of Myc in adaptive expansion of beta cells Methods: Islets were isolated from 8 week old or one year old male C57BL6 mice fed a standard or high fat diet. RNAseq and DNA mehtylseq was performed. Results: RNAseq showed that Myc target genes are upregulted in young, but not old mice after a short term high fat diet. DNA methylation analysis shows hypomethylation of cell cycle genes that are Myc targets in islets from young mice fed with a HFD. more...

Organism:: Mus musculus

Type:: Expression profiling by high throughput sequencing; Methylation profiling by high throughput sequencing

Platforms:: GPL17021 GPL16417
29 Samples

Download data: TXT

Series

Accession:: GSE131941

ID:: 200131941

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 1000170212.

Illumina HiSeq 2500 (Mus musculus)

Organism:: Mus musculus

11417 Series
305308 Samples

Platform

Accession:: GPL17021

ID:: 100017021

Select item 3038313143.

Old HFD 4 RNAseq

Organism:: Mus musculus

Source name:: Islets

Platform:: GPL17021
Series:: GSE131941

Sample

Accession:: GSM3831314

ID:: 303831314

SRA Run Selector

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GSM3831314[Accession] (3)
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