GSM3538393[Accession] - GEO DataSets

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Items: 4

Select item 2001246441.

Combination Targeting of the Bromodomain and Acetyltransferase Active Site of p300/CBP

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Homo sapiens

Type:: Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by high throughput sequencing

Platform:: GPL18573
18 Samples

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Series

Accession:: GSE124644

ID:: 200124644

PubMed Full text in PMC Similar studies

Select item 2001246432.

Combination Targeting of the Bromodomain and Acetyltransferase Active Site of p300/CBP [RNA-seq]

(Submitter supplied) p300 and CBP are highly related histone acetyltransferase (HAT) enzymes that regulate gene expression, and their dysregulation has been linked to cancer and other diseases. p300/CBP is composed of a number of domains including a HAT domain which is inhibited by the small molecule A-485 and an acetyl-lysine binding bromodomain which was recently found to be selectively antagonized by the small molecule I-CBP112. more...