GEO DataSets

(Submitter supplied) Human fibroblasts can be induced into pluripotent stem cells (iPS cells), but the reprogramming efficiency is quite low. Here, we screened a panel of candidate factors in the presence of OCT4, SOX2, KLF4 and c-MYC in an effort to improve the reprogramming efficiency from human adult fibroblasts. We found that p53 siRNA and UTF1 enhanced the efficiency of iPS cell generation up to 100-fold, even when the oncogene c-MYC was removed from the combinations. more...

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL6254

33 Samples

Download data: GPR, TIFF, XLS

(Submitter supplied) Phalanx Biotech Group's Human OneArray contains 32,048 features, 30968 detection probes and 1080 control probes, spotted onto glass slides using a proprietary non-contact printing method. Detection probes are annotated against the human genome and grouped into the following categories: Group 1 - gene specific: exon Group 2 - intron hit Group 3 - intergenic Group 4 - multi-gene hits Group 5 - no hit to genome Group 6 - >200 hits to genome Protocol: See http://www.phalanxbiotech.com/ for updated protocols

Organism:

Homo sapiens

41 Series

2 Related Platforms

653 Samples

Download data