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Items: 4

1.

Genome-wide CRISPR-Cas9 interrogation of splicing networks reveals a mechanism for recognition of autism-misregulated neuronal microexons

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
synthetic construct; Mus musculus
Type:
Expression profiling by high throughput sequencing; Other
4 related Platforms
122 Samples
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Series
Accession:
GSE112601
ID:
200112601
2.

Genome-wide CRISPR-Cas9 interrogation of splicing networks reveals a mechanism for recognition of autism-misregulated neuronal microexons [CRISPR screen]

(Submitter supplied) Alternative splicing has critical roles in diverse cellular, developmental and pathological processes. However, the full repertoires of factors that control individual splicing events are not known. We describe a CRISPR-based screening strategy for the systematic identification of genes that control 3-27 nt microexons with functions in nervous system development and that are commonly disrupted in autism. more...
Organism:
synthetic construct; Mus musculus
Type:
Other
Platforms:
GPL19057 GPL19424
49 Samples
Download data: TAB, XLSX
Series
Accession:
GSE112599
ID:
200112599
3.

Illumina NextSeq 500 (Mus musculus)

Platform
Accession:
GPL19057
ID:
100019057
4.

Shank2 splicing reporter, sorted cells with 2% lowest EGFP/mCherry, replicate 5 (T24)

Organism:
Mus musculus
Source name:
Neuroblastoma cells
Platform:
GPL19057
Series:
GSE112599 GSE112601
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Sample
Accession:
GSM3073845
ID:
303073845
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