GSM3058320[Accession] - GEO DataSets

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Items: 4

Select item 2001121361.

Mammalian ISWI and SWI/SNF selectively mediate binding of distinct groups of transcription factors

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Mus musculus

Type:: Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by high throughput sequencing; Methylation profiling by high throughput sequencing; Other

Platforms:: GPL19057 GPL17021
90 Samples

Download data: BED, MATRIX, TSV, WIG

Series

Accession:: GSE112136

ID:: 200112136

PubMed Full text in PMC Similar studies

Select item 2001121302.

Mammalian ISWI and SWI/SNF selectively mediate binding of distinct groups of transcription factors (ATAC-seq data sets)

(Submitter supplied) Remodelers define nucleosome composition, presence and position. Mammalian imitation-switch-type (ISWI) comprise one class, mostly relying on the ATPase Snf2h for activity. We show that embryonic stem cells are viable without Snf2h, enabling to study its function and contrast it to Brg1, the ATPase of SWI/SNF. Loss of Snf2h specifically affects nucleosomal positioning and increases linker lengths genome-wide providing in vivo evidence for ISWI function in ruling nucleosomal spacing. more...