GSM2679704[Accession] - GEO DataSets

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Items: 4

Select item 2001003771.

HIV-1 infection of human monocyte-derived dendritic cells with and without the integrase inhibitor, Raltegravir

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Homo sapiens

Type:: Expression profiling by array; Genome binding/occupancy profiling by high throughput sequencing

Platforms:: GPL17077 GPL18573
56 Samples

Download data: BW, TXT

Series

Accession:: GSE100377

ID:: 200100377

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2001003742.

HIV-1 infection of human monocyte-derived dendritic cells with and without the integrase inhibitor, Raltegravir (gene expression).

(Submitter supplied) Myeloid dendritic cells (DCs) have the innate capacity to sense pathogens and orchestrate immune responses. However, DCs do not mount efficient immune responses to HIV-1, due to potent restriction at the level of reverse transcription. Here, we uncover that when reverse transcription is allowed to proceed, DCs detect HIV-1 in distinct phases, before and after integration. Blocking integration suppressed, but did not abolish, activation of the transcription factor, IRF3, interferon responses, and DC maturation. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL17077
32 Samples

Download data: TXT

Series

Accession:: GSE100374

ID:: 200100374

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 1000170773.

Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Probe Name version)

(Submitter supplied) SurePrint G3 Human GE v2 8x60K Microarray Design ID: 039494 Design Format: 8 x 60 K Control Grid: IS-62976-8-V2_60kby8_GX_EQC_201000210 Build Version: hg19:GRCh37:Feb2009 Arrays of this design have barcodes that begin with 16039494 or 2539494. Orientation: Features are numbered numbered Left-to-Right, Top-to-Bottom as scanned by an Agilent scanner (barcode on the left, DNA on the back surface, scanned through the glass), matching the FeatureNum output from Agilent's Feature Extraction software. more...