GSM2666780[Accession] - GEO DataSets

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Items: 4

Select item 2000999781.

Thiol-linked alkylation for the metabolic sequencing of RNA

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: synthetic construct; Mus musculus

Type:: Expression profiling by high throughput sequencing; Other; Non-coding RNA profiling by high throughput sequencing

Platforms:: GPL19604 GPL17021
141 Samples

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Series

Accession:: GSE99978

ID:: 200099978

PubMed Full text in PMC Similar studies

Select item 2000999692.

Thiol-linked alkylation for the metabolic sequencing of RNA [Primer Extension Assays]

(Submitter supplied) Gene expression profiling by high-throughput sequencing reveals qualitative and quantitative changes in RNA species at steady-state but obscures the intracellular dynamics of RNA transcription, processing and decay. We developed thiol(SH)-linked alkylation for the metabolic sequencing of RNA (SLAM-seq), an orthogonal chemistry-based epitranscriptomics-sequencing technology that uncovers 4-thiouridine (s4U)-incorporation in RNA species at single-nucleotide resolution. more...