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Items: 4

1.

Synergistic Immunostimulatory Effects and Therapeutic Benefit of Combined Histone Deacetylase and Bromodomain Inhibition in Non-small Cell Lung Cancer.

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Mus musculus
Type:
Expression profiling by array; Expression profiling by high throughput sequencing
Platforms:
GPL19057 GPL22364
204 Samples
Download data: RCC
Series
Accession:
GSE98049
ID:
200098049
2.

Single-cell profiling of tumor infiltrating T cells and macrophages [Nanostring]

(Submitter supplied) Effective therapies for non-small cell lung cancer (NSCLC) remain challenging despite an increasingly comprehensive understanding of somatically altered oncogenic pathways. It is now clear that therapeutic agents with potential to impact the tumor immune microenvironment potentiate immune-orchestrated therapeutic benefit. Herein we evaluated the immunoregulatory properties of histone deacetylase (HDAC) and bromodomain inhibitors, two classes of drugs that modulate the epigenome, with a focus on key cell subsets that are engaged in an immune response. more...
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL22364
12 Samples
Download data: RCC
Series
Accession:
GSE98044
ID:
200098044
3.

nCounter Mouse PanCancer Immune Profiling Panel

(Submitter supplied) See manufacturer's website (http://www.nanostring.com) http://www.nanostring.com/media/pdf/MAN_nCounter_Gene_Expression_Assay.pdf
Organism:
Mus musculus
26 Series
442 Samples
Download data
Platform
Accession:
GPL22364
ID:
100022364
4.

Ricolinostat-treated macrophages[DA_19_9.RCC]

Organism:
Mus musculus
Source name:
Macrophages
Platform:
GPL22364
Series:
GSE98044 GSE98049
Download data: RCC
Sample
Accession:
GSM2585958
ID:
302585958
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