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Items: 3

1.

A histone mimic within DNA Ligase 1 links DNA replication and DNA remethylation: a revised model for the maintenance of DNA methylation by UHRF (RRBS)

(Submitter supplied) DNA methylation is an essential epigenetic mark in mammals, and its pattern has to be re-established after each round of DNA replication. The protein UHRF1 is known to be necessary for this process, but its mode of action is unclear. Using proteomics, we havefound that a replication factor, DNA Ligase 1 (LIG1), is a direct interactor of UHRF1. The interaction is mediated bythe Tudor domain of UHRF1 and an H3K9-like histone mimic within LIG1. more...
Organism:
Mus musculus
Type:
Methylation profiling by high throughput sequencing
Platform:
GPL21103
6 Samples
Download data: BEDGRAPH
Series
Accession:
GSE89819
ID:
200089819
2.

Illumina HiSeq 4000 (Mus musculus)

Platform
Accession:
GPL21103
ID:
100021103
3.

E14 Np95-/- RRBS

Organism:
Mus musculus
Source name:
ES-E14
Platform:
GPL21103
Series:
GSE89819
Download data: BEDGRAPH
Sample
Accession:
GSM2390046
ID:
302390046
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db=gds|term=GSM2390046[Accession]|query=1|qty=2|blobid=MCID_67ab9a0585cceb1995bcfa8e|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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