GSM2175037[Accession] - GEO DataSets

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Items: 4

Select item 2000818841.

Multiplexed engineering and analysis of endogenous enhancer activity in single cells

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Homo sapiens; Mus musculus

Type:: Expression profiling by high throughput sequencing

Platforms:: GPL19415 GPL18573
134 Samples

Download data: TXT

Series

Accession:: GSE81884

ID:: 200081884

PubMed Similar studies

Select item 2000817472.

Multiplexed engineering and analysis of endogenous enhancer activity in single cells: Mosaic-Seq of beta-globin locus (pooled infection)

(Submitter supplied) Transcriptional enhancers orchestrate cell-type specific gene expression programs critical to eukaryotic development, physiology, and disease. However, despite the large number of enhancers now identified, only a small number have been functionally assessed. Here, we develop MOsaic Single-cell Analysis by Indexed CRISPR Sequencing (Mosaic-seq), a method that measures one direct phenotype of enhancer repression: change of the transcriptome, at the single cell level. more...