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Items: 3

1.

Activin/Smad2-induced H3K27me3 reduction is crucial to initiate mesendoderm differentiation of ES Cells

(Submitter supplied) Mesendoderm (ME) differentiation of human embryonic stem cells (hESCs) is directed by various extrinsic signals together with intrinsic epigenetic modifications. However, the dynamics of epigenetic modifications and their regulation to initiate ME differentiation remain elusive. In this study, we report that H3K27me3 is decreased during ME initiation, which is essential for the subsequent differentiation by collaborative effects of Activin and Wnt signaling. more...
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing
Platform:
GPL11154
16 Samples
Download data: BW, TXT
Series
Accession:
GSE81617
ID:
200081617

PubMed Full text in PMC Similar studies Analyze with GEO2RSRA Run Selector

2.

Illumina HiSeq 2000 (Homo sapiens)

Organism:
Homo sapiens
10670 Series
185707 Samples
Download data
Platform
Accession:
GPL11154
ID:
100011154

3.

Activin A + Wnt3a 6h H3K27me3 ChIP-seq

Organism:
Homo sapiens
Source name:
H1-hESC
Platform:
GPL11154
Series:
GSE81617
Download data: BW
Sample
Accession:
GSM2159752
ID:
302159752

SRA Run Selector

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db=gds|term=GSM2159752[Accession]|query=1|qty=2|blobid=MCID_67dd9c2373a8307cd8ec4c20|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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