GSM2154787[Accession] - GEO DataSets

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Items: 4

Select item 2000814901.

In fetal testis, SOX9 acts on transcription and splicing of its targets genes through binding to genomic regions with conserved signatures

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Mus musculus; Bos taurus

Type:: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing

Platforms:: GPL13112 GPL18480 GPL15749
15 Samples

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Accession:: GSE81490

ID:: 200081490

Select item 2000814892.

In fetal testis, SOX9 acts on transcription and splicing of its targets genes through binding to genomic regions with conserved signatures [RNA-seq]

(Submitter supplied) In mammals, male fate is under the control of the master transcriptional regulator, SOX9: in its presence, somatic precursor cells of the embryonic gonads differentiate into Sertoli cells, the main organizers of testicular differentiation. Therefore, analyzing target genes of this transcription factor allows understanding mechanisms of cellular commitment at the genomic level. With the use of ChIP-seq in murine and bovine wild-type testes combined with RNAseq from mouse testes lacking SOX9, we identified SOX9 target genes in the mammalian fetal gonad. more...