GSM2090426[Accession] - GEO DataSets

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Items: 4

Select item 2000792901.

BET bromodomain proteins function as master transcription elongation factors independent of CDK9 recruitment

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Homo sapiens

Type:: Expression profiling by high throughput sequencing; Methylation profiling by high throughput sequencing; Other

Platform:: GPL18573
58 Samples

Download data: BEDGRAPH, WIG

Series

Accession:: GSE79290

ID:: 200079290

Select item 2000792712.

BET bromodomain proteins function as master transcription elongation factors independent of CDK9 recruitment [NET-seq]

(Submitter supplied) Cancer arises from the malignant interplay between oncogenic signaling and cell specification. Transcriptionally activated stem, growth and survival programs reshape an epigenomic identity defined by a transcriptional core regulatory circuitry. To study and disrupt oncogenic transcription, we first created inhibitors of BET bromodomains. Selective antagonism of oncogenic transcriptional signaling arises from bromodomain-specific activity. more...