GSM1975480[Accession] - GEO DataSets

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Items: 4

Select item 2000761631.

Gene expression profiling in human precision-cut liver slices upon treatment with the FXR agonist obeticholic acid

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Homo sapiens; Mus musculus

Type:: Expression profiling by array

Platforms:: GPL11532 GPL11533
30 Samples

Download data: CEL

Series

Accession:: GSE76163

ID:: 200076163

Select item 2000761612.

Gene expression profiling in human precision-cut liver slices upon treatment with the FXR agonist obeticholic acid [human]

(Submitter supplied) Background: The bile acid-activated farnesoid X receptor (FXR) is a nuclear receptor regulating bile acid, glucose and cholesterol homeostasis. Obeticholic acid (OCA; also known as INT-747 or 6α-ethyl-chenodeoxycholic acid), a promising drug for the treatment of non-alcoholic steatohepatitis (NASH) and type 2 diabetes, activates FXR. Mouse studies demonstrated that FXR activation by OCA (INT-747) alters hepatic expression of many genes. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL11532
6 Samples

Download data: CEL

Series

Accession:: GSE76161

ID:: 200076161

Select item 1000115323.

[HuGene-1_1-st] Affymetrix Human Gene 1.1 ST Array [transcript (gene) version]

(Submitter supplied) HuGene-1_1-st-v1.na32.hg19.transcript.csv #%create_date=Tue Jun 21 17:41:46 2011 PDT #%chip_type=HuGene-1_1-st-v1 #%lib_set_name=HuGene-1_1-st #%lib_set_version=v1 #%genome-species=Homo sapiens #%genome-version=hg19 #%genome-version-ucsc=hg19 #%genome-version-ncbi=GRCh37 #%genome-version-create_date=2009-02-00 #%genome-lifted-method=liftOver #%genome-lifted_from-species=Homo sapiens #%genome-lifted_from-version-ucsc=hg18 #%genome-lifted_from-version-ncbi=36.1 #%netaffx-annotation-date=2011-06-22 #%netaffx-annotation-netaffx-build=32 Protocol: see manufacturer's web site