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Items: 4

1.

Expression data from IGF-I-stimulated MCF-7 cells

(Submitter supplied) Substantial evidence implicates IGF-I signaling in the development and progression of breast cancer. To identify transcriptional targets of IGF action in breast cancer cells, we performed gene expression profiling (>22,000 RNA transcripts) of IGF-I-stimulated MCF-7 cells, a well characterized breast cancer cell line that is highly responsive to IGFs. We defined an IGF-I gene signature pattern of hundreds of genes either up-regulated or down-regulated at both 3 and 24 hrs in vitro. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Dataset:
GDS3484
Platform:
GPL571
11 Samples
Download data: CEL
Series
Accession:
GSE7561
ID:
200007561
2.
Full record GDS3484

Insulin-like growth factor-I effect on breast cancer cell line: time course

Analysis of breast cancer MCF-7 cells stimulated with insulin-like growth factor-I (IGF-I) for 3 or 24 hours. High serum IGF-I levels are associated with an elevated risk of breast cancer. Results provide insight into the role of IGF-1 in the development and progression of breast cancer.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 2 agent, 2 time sets
Platform:
GPL571
Series:
GSE7561
11 Samples
Download data: CEL
3.

[HG-U133A_2] Affymetrix Human Genome U133A 2.0 Array

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 08, 2012: annotation table updated with netaffx build 32 July 01, 2016: annotation table updated with netaffx build 35 Protocol: see manufacturer's web site The GeneChip Human Genome U133A 2.0 Array is a single array representing 14,500 well-characterized human genes that can be used to explore human biology and disease processes. more...
Organism:
Homo sapiens
84 DataSets
641 Series
12 Related Platforms
24467 Samples
Download data
Platform
Accession:
GPL571
ID:
100000571
4.

IGF-treated cells (24hr), biological rep3

Organism:
Homo sapiens
Source name:
MCF-7
Platform:
GPL571
Series:
GSE7561
Dataset:
GDS3484
Download data: CEL
Sample
Accession:
GSM183431
ID:
300183431
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