GSM1551883[Accession] - GEO DataSets

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Items: 4

Select item 2000635341.

Transcriptome profiling of TALEN-mediated LATS2 knockout HeLa-S3 cells

(Submitter supplied) Chromatin modifying activities for construction of appropriate epigenetic landscapes by polycomb repressive complex 2 (PRC2) play an essential role in development and tumorigenesis. However, the spatiotemporal mechanisms by which PRC2 achieves diverse epigenomes for specific tissue or cellular contexts remain poorly understood. Here, we discovered that LATS2 knockout causes dysregulation of PRC2 and subsequent transcriptome changes for differentiation in both mouse and human cells. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL13607
3 Samples

Download data: TXT

Series

Accession:: GSE63534

ID:: 200063534

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000635382.

LATS2 regulates repressive epigenetic integrity via regulation of Polycomb repressive complex 2

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Homo sapiens; Mus musculus

Type:: Expression profiling by high throughput sequencing; Expression profiling by array; Non-coding RNA profiling by array; Genome binding/occupancy profiling by high throughput sequencing

6 related Platforms
36 Samples

Download data: BW, TXT

Series

Accession:: GSE63538

ID:: 200063538

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 1000136073.

Agilent-028004 SurePrint G3 Human GE 8x60K Microarray (Feature Number version)

(Submitter supplied) SurePrint G3 Human GE 8x60K Microarray Arrays of this design have barcodes that begin with 16028004 or 2528004. Orientation: Features are numbered numbered Left-to-Right, Top-to-Bottom as scanned by an Agilent scanner (barcode on the left, DNA on the back surface, scanned through the glass), matching the FeatureNum output from Agilent's Feature Extraction software. The ID column represents the Agilent Feature Extraction feature number. more...