GSM1380301[Accession] - GEO DataSets

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Items: 4

Select item 2000573431.

Immune regulation by low doses of the DNA methyltransferase inhibitor 5-azacitidine in common human epithelial cancers

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Homo sapiens

Type:: Expression profiling by array; Methylation profiling by array

Platforms:: GPL13534 GPL4133
575 Samples

Download data: TXT

Series

Accession:: GSE57343

ID:: 200057343

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000573412.

Effect of AZA on gene expression of multiple breast, colon, and ovarian cell lines [expression]

(Submitter supplied) Epigenetic therapy is emerging as a potential therapy for solid tumors. To investigate its mechanism of action, we performed integrative expression and methylation analysis of 63 cancer cell lines (breast, colorectal, and ovarian) after treatment with the DNA methyltransferase inhibitor 5-azacitidine (AZA). Gene Set Enrichment Analysis demonstrated significant enrichment for immunomodulatory pathways in all three cancers (14.4-31.3%) including interferon signaling, antigen processing and presentation, and cytokines/chemokines. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL4133
237 Samples

Download data: TXT

Series

Accession:: GSE57341

ID:: 200057341

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 1000041333.

Agilent-014850 Whole Human Genome Microarray 4x44K G4112F (Feature Number version)

(Submitter supplied) This multi-pack (4X44K) formatted microarray represents a compiled view of the human genome as it is understood today. The sequence information used to design this product was derived from a broad survey of well known sources such as RefSeq, Goldenpath, Ensembl, Unigene and others. The resulting view of the human genome covers 41K unique genes and transcripts which have been verified and optimized by alignment to the human genome assembly and by Agilent's Empirical Validation process. more...